DHEA for osteoporosis

One fairly clear-cut benefit of supplementation of the adrenal gland hormone, DHEA, is increased bone density.

Here's one study showing very persuasive effects of DHEA supplementation, 50 mg per day for 12 months, on bone density: Effects of Dehydroepiandrosterone Replacement Therapy on Bone Mineral Density in Older Adults: A Randomized, Controlled Trial

70 men and 70 women were given DHEA 50 mg per day vs. placebo with pre- and post- measures of bone density made.








































From Jankowski CM et al. J Clin Endocrinol Metab 2006 Aug;91(8):2986-93.



As you can see, the women responded more vigorously than the men.






From Jankowski CM et al. J Clin Endocrinol Metab 2006 Aug;91(8):2986-93.





To achieve these results, women increased DHEA blood levels to 225-300 mcg/dl, while men increased DHEA blood levels to 300-400 mcg/dl.


This study corroborates findings made by a Washington University group and that of a University of California group that also showed increased bone with DHEA supplementation.